基础论坛:Hierarchical Connectome Modes and Critical State Jointly Maximize Human Brain Functional Diversity

文:基础与前沿研究院 图:基础与前沿研究院 / 来源:基础与前沿研究院 / 2019-06-11 / 点击量:600

  由基础与前沿研究院主办的“基础论坛”第176期邀请到香港浸会大学物理系周昌松教授来校作学术交流。具体安排如下,欢迎师生们参加。

  时 间:2019年6月17日(周一)上午10:00

  地 点:沙河校区通信楼725会议室

  报告人:周昌松(香港浸会大学物理系教授)

  报告题目:Hierarchical Connectome Modes and Critical State Jointly Maximize Human Brain Functional Diversity

周昌松.jpg

  报告摘要:

  The brain requires diverse segregated and integrated processing to perform normal functions in terms of anatomical structure and self-organized dynamics with critical features, but the fundamental relationships between the complex structural connectome, critical state and functional diversity remain unknown. Herein, we extend eigenmode analysis to investigate the joint contribution of hierarchical modular structural organization and critical state to brain functional diversity. We show that the structural modes inherent to the hierarchical modular structural connectome allow a nested functional segregation and integration across multiple spatiotemporal scales. The real brain hierarchical modular organization provides large structural capacity for diverse functional interactions, which are generated by sequentially activating and recruiting the hierarchical connectome modes, and the critical state can best explore the capacity to maximize the functional diversity. Our results reveal structural and dynamical mechanisms that jointly support a balanced segregated and integrated brain processing with diverse functional interactions, and they also shed light on dysfunctional segregation and integration in neurodegenerative diseases and neuropsychiatric disorders.

  主讲人简介:

  周昌松,物理学博士,香港浸会大学物理系教授,浸会大学非线性研究中心及北京-香港-新加坡非线性复杂系统联合中心主任。1992年获南开大学物理学士, 1997年获南开大学物理博士,1997-2007年在新加坡、香港、德国等地从事访问研究,洪堡基金获得者。2007年加入香港浸会大学物理系, 2011年获浸会大学“杰出青年研究者校长奖”。

  致力于复杂系统动力学基础研究及其应用,特别是网络的复杂联结结构与体系的动态行为的关系和相互作用。近几年一直与国际国内系统和认知神经科学家紧密合作,把这些理论进展应用到大脑的复杂联结结构和活动以及认知功能及障碍的分析和建模等方面研究中。在国际交叉学术刊物PNAS等发表论文130余篇。SCI引用8300余次,H-因子为36 (Google Scholar引用12900余次,H-因子为44)。任Scientific Reports编委, PLoS One, Cognitive Neurodynamics学术编辑及多种国际期刊常任审稿人。


编辑:王晓刚  / 审核:李果  / 发布者:陈伟